Document Type

Thesis

Degree Name

Master of Science (MSc)

Department

Health Science

Faculty/School

Faculty of Science

First Advisor

Dr. Todd Coleman

Advisor Role

Thesis Supervisor

Second Advisor

Dr. Ketan Shankardass

Advisor Role

Committee Member

Third Advisor

Dr. Ciann Wilson

Advisor Role

Committee Member

Abstract

Background: Several social and environmental factors influence drug use behaviors and contribute to frequent drug use among Two-Spirit, Lesbian, Gay, Bisexual, Transgender, Queer, and other (2SLGBTQ+) individuals. The purpose of the current study was to examine the relationship between the minority stress, drug use, and other socio-ecological factors.

Methods: This study employed structural equation modelling on data (2021—2022) from a nationally representative pan-Canadian survey (N = 1542) on 2SLGBTQ+ health to examine the association between minority stress, drug use, and relevant socio-ecological predictors. A separate mediation analysis was conducted and controlled for socio-demographic characteristics.

Results: SEM results showed parsimonious fit of data [chi-square = 526.86 (df = 61, p < 0.0001), SRMR = 0.04, RMSEA = 0.07 (95% CI = 0.07, 0.08), AGFI = 0.92, and CFI = 0.95]. The direct path of minority stress on drug use was significant (β = 0.07899, p = 0.0005) and other indirect effects were observed. Psychological distress significantly mediated the relationship through an indirect pathway (β = 0.07, p < 0.0001).

Conclusions: Minority stress and drug use are inter-related through direct and indirect paths and psychological distress plays a crucial role in mediation. Study findings add valuable insight to the field of substance use and addiction by deepening our understanding of the mechanisms behind drug use in the population.

Convocation Year

2026

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